4u6r: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of human IRE1 cytoplasmic domains in complex with a sulfonamide inhibitor.==
 
<StructureSection load='4u6r' size='340' side='right' caption='[[4u6r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
The entry 4u6r is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4u6r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U6R FirstGlance]. <br>
Authors: Mohr, C.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3E4:N-{4-[(3-{2-[(TRANS-4-AMINOCYCLOHEXYL)AMINO]PYRIMIDIN-4-YL}PYRIDIN-2-YL)OXY]-3-METHYLNAPHTHALEN-1-YL}-2-CHLOROBENZENESULFONAMIDE'>3E4</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4u79|4u79]]</td></tr>
Description: Crystal structure of human IRE1 cytoplasmic domains in complex with a sulfonamide inhibitor.
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u6r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u6r RCSB], [http://www.ebi.ac.uk/pdbsum/4u6r PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Mohr, C.]]
[[Category: Endoribonuclease]]
[[Category: Hydrolase]]
[[Category: Kinase]]
[[Category: Transferase]]