4ux6: Difference between revisions

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'''Unreleased structure'''
==The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)==
 
<StructureSection load='4ux6' size='340' side='right' caption='[[4ux6]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
The entry 4ux6 is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ux6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UX6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UX6 FirstGlance]. <br>
Authors: Cheshire, D.R., Andrews, G., Beaton, H.G., Birkinshaw, T., Boughton-Smith, N., Connolly, S., Cook, T.R., Cooper, A., Cooper, S.L., Cox, D., Dixon, J., Gensmantel, N., Hamley, P.J., Harrison, R., Hartopp, P., Kack, H., Luker, T., Mete, A., Millichip, I., Nicholls, D.J., Pimm, A.D., St-Gallay, S.A., Wallace, A.V.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=YWO:O-(5-METHYL-2-NITROPHENYL)-D-TYROSINAMIDE'>YWO</scene></td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Nitric-oxide_synthase_(NADPH_dependent) Nitric-oxide synthase (NADPH dependent)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] </span></td></tr>
Description: The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ux6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ux6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ux6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ux6 PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Andrews, G.]]
[[Category: Beaton, H G.]]
[[Category: Birkinshaw, T.]]
[[Category: Boughton-Smith, N.]]
[[Category: Cheshire, D R.]]
[[Category: Connolly, S.]]
[[Category: Cook, T R.]]
[[Category: Cooper, A.]]
[[Category: Cooper, S L.]]
[[Category: Cox, D.]]
[[Category: Dixon, J.]]
[[Category: Gensmantel, N.]]
[[Category: Hamley, P J.]]
[[Category: Harrison, R.]]
[[Category: Hartopp, P.]]
[[Category: Kack, H.]]
[[Category: Luker, T.]]
[[Category: Mete, A.]]
[[Category: Millichip, I.]]
[[Category: Nicholls, D J.]]
[[Category: Pimm, A D.]]
[[Category: St-Gallay, S A.]]
[[Category: Wallace, A V.]]
[[Category: Drug design]]
[[Category: Oxidoreductase]]

Revision as of 07:58, 8 October 2014

The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)

4ux6, resolution 3.00Å

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