211d: Difference between revisions

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[[~~Image~~:~~211d~~.~~png~~|~~left~~|~~200px~~]]

==THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE==

== Structural highlights ==

<table><tr><td colspan='2'>[[211d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211D FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=211d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=211d RCSB], [http://www.ebi.ac.uk/pdbsum/211d PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.

~~{{STRUCTURE_211d| PDB=211d | SCENE= }}~~

Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.,Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550<ref>PMID:7492550</ref>

~~===THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE===~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~{{ABSTRACT_PUBMED_7492550}}~~

== References ==

==~~About this Structure~~==

__TOC__

~~[[211d]] is a 1 chain structure. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA].~~

</StructureSection>

[[Category: Arvantis, G M.]]

[[Category: Berman, H M.]]

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@@ Line 1: / Line 1: @@
-[[Image:211d.png|left|200px]]
+==THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE==
+<StructureSection load='211d' size='340' side='right' caption='[[211d]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[211d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211D FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=211d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=211d RCSB], [http://www.ebi.ac.uk/pdbsum/211d PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.
-{{STRUCTURE_211d|  PDB=211d  |  SCENE=  }}
+Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.,Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550<ref>PMID:7492550</ref>
-===THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE===
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-{{ABSTRACT_PUBMED_7492550}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[211d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA].
+</StructureSection>
 [[Category: Arvantis, G M.]]
 [[Category: Berman, H M.]]