1jiz: Difference between revisions

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[[Image:1jiz.gif|left|200px]]~~<br /><applet load~~="1jiz~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1jiz.gif|left|200px]]

~~caption="~~1jiz, resolution 2.60Å" />

'''Crystal Structure Analysis of human Macrophage Elastase MMP-12'''~~<br />~~

{{Structure

|PDB= 1jiz |SIZE=350|CAPTION= <scene name='initialview01'>1jiz</scene>, resolution 2.60Å

|SITE=

|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CGS:N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE'>CGS</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65]

|GENE=

}}

'''Crystal Structure Analysis of human Macrophage Elastase MMP-12'''

==Overview==

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==About this Structure==

1JIZ is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CGS:'>CGS</scene> as [http://en.wikipedia~~.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIZ OCA].

1JIZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIZ OCA].

==Reference==

Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor., Nar H, Werle K, Bauer MM, Dollinger H, Jung B, J Mol Biol. 2001 Sep 28;312(4):743-51. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~11575929 11575929]

Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor., Nar H, Werle K, Bauer MM, Dollinger H, Jung B, J Mol Biol. 2001 Sep 28;312(4):743-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11575929 11575929]

[[Category: Homo sapiens]]

[[Category: Macrophage elastase]]

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[[Category: mmp-12]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:04:13 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1jiz.gif|left|200px]]<br /><applet load="1jiz" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1jiz.gif|left|200px]]
-caption="1jiz, resolution 2.60&Aring;" />
-'''Crystal Structure Analysis of human Macrophage Elastase MMP-12'''<br />
+ {{Structure
+|PDB= 1jiz |SIZE=350|CAPTION= <scene name='initialview01'>1jiz</scene>, resolution 2.60&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CGS:N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE'>CGS</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65]
+|GENE=
+}}
+'''Crystal Structure Analysis of human Macrophage Elastase MMP-12'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-JIZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CGS:'>CGS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIZ OCA].
+JIZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JIZ OCA].
 ==Reference==
-Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor., Nar H, Werle K, Bauer MM, Dollinger H, Jung B, J Mol Biol. 2001 Sep 28;312(4):743-51. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11575929 11575929]
+Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor., Nar H, Werle K, Bauer MM, Dollinger H, Jung B, J Mol Biol. 2001 Sep 28;312(4):743-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11575929 11575929]
 [[Category: Homo sapiens]]
 [[Category: Macrophage elastase]]
@@ Line 29: / Line 38: @@
 [[Category: mmp-12]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:23:12 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:04:13 2008''