2k98: Difference between revisions

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[[~~Image~~:2k98.~~png|left|200px~~]]

==Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle==

== Structural highlights ==

<table><tr><td colspan='2'>[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K98 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k98 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k98 RCSB], [http://www.ebi.ac.uk/pdbsum/2k98 PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

Essential understanding: Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.

~~{{STRUCTURE_2k98| PDB=2k98 | SCENE= }}~~

Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy.,Bhunia A, Ramamoorthy A, Bhattacharjya S Chemistry. 2009 Jan 29;15(9):2036-2040. PMID:19180607<ref>PMID:19180607</ref>

~~===Helical hairpin structure~~ of ~~potent antimicrobial peptide MSI-594 in~~ the ~~presence of Lipopolysaccharide micelle===~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~{{ABSTRACT_PUBMED_19180607}}~~

== References ==

~~==About this Structure==~~

__TOC__

~~[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2K98 OCA].~~

</StructureSection>

==~~Reference~~==

<~~ref group="xtra">PMID:019180607<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Bhattacharjya, S.]]

[[Category: Bhunia, A.]]

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@@ Line 1: / Line 1: @@
-[[Image:2k98.png|left|200px]]
+==Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle==
+<StructureSection load='2k98' size='340' side='right' caption='[[2k98]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K98 FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k98 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k98 RCSB], [http://www.ebi.ac.uk/pdbsum/2k98 PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Essential understanding: Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.
-{{STRUCTURE_2k98|  PDB=2k98  |  SCENE=  }}
+Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy.,Bhunia A, Ramamoorthy A, Bhattacharjya S Chemistry. 2009 Jan 29;15(9):2036-2040. PMID:19180607<ref>PMID:19180607</ref>
-===Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle===
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-{{ABSTRACT_PUBMED_19180607}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:019180607</ref><references group="xtra"/>
 [[Category: Bhattacharjya, S.]]
 [[Category: Bhunia, A.]]