VP24: Difference between revisions

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== Structural Characteristics ==

The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal ~~shape~~, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning.

The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal shaped domain, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning.

<scene name='60/602719/Reston_vp24/1'>Ebola Structure</scene> (Reston)

There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin.

There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin. An α helix formed by the N-terminus runs from the top of the "pyramid" to one of the pockets located underneath the "pyramid."

<scene name='60/602719/Marburg_vp24/1'>Marburg Structure</scene>

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@@ Line 16: / Line 16: @@
 == Structural Characteristics ==
-The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal shape, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning.
+The Ebola and Marburg VP24 proteins are 30% identical. They share a similar pyramidal shaped domain, as well as a few structures. Both viruses have two highly conserved pockets underneath the "pyramid's" base. Additionally, the N termini of Ebola (Zaire) and the Marburg virus are very similar in function. They are used by the for proper nucleocapsid functioning.
 <scene name='60/602719/Reston_vp24/1'>Ebola Structure</scene> (Reston)
-There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin.
+There are a few structural characteristics only found in the Ebola viruses. At the top of the pyramidal domain, there are α helices present which are thought to interact with the α karyopherin. An α helix formed by the N-terminus runs from the top of the "pyramid" to one of the pockets located underneath the "pyramid."
 <scene name='60/602719/Marburg_vp24/1'>Marburg Structure</scene>