2w8m: Difference between revisions

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[[~~Image~~:2w8m.~~png|left|200px~~]]

==STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.==

== Structural highlights ==

<table><tr><td colspan='2'>[[2w8m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W8M FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w8m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w8m RCSB], [http://www.ebi.ac.uk/pdbsum/2w8m PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

Structural studies have made significant contributions to our understanding of Sulfolobus spindle-shaped viruses (Fuselloviridae), an important model system for archaeal viruses. Continuing these efforts, we report the structure of D212 from Sulfolobus spindle-shaped virus Ragged Hills. The overall fold and conservation of active site residues place D212 in the PD-(D/E)XK nuclease superfamily. The greatest structural similarity is found to the archaeal Holliday junction cleavage enzymes, strongly suggesting a role in DNA replication, repair, or recombination. Other roles associated with nuclease activity are also considered.

~~{{STRUCTURE_2w8m| PDB=2w8m | SCENE= }}~~

The crystal structure of D212 from sulfolobus spindle-shaped virus ragged hills reveals a new member of the PD-(D/E)XK nuclease superfamily.,Menon SK, Eilers BJ, Young MJ, Lawrence CM J Virol. 2010 Jun;84(12):5890-7. Epub 2010 Apr 7. PMID:20375162<ref>PMID:20375162</ref>

~~===STRUCTURE OF D212~~, ~~A NUCLEASE FROM A FUSSELOVIRUS.===~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~{{ABSTRACT_PUBMED_20375162}}~~

== References ==

~~==About this Structure==~~

__TOC__

~~[[2w8m]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA].~~

</StructureSection>

==~~Reference~~==

<~~ref group="xtra">PMID:020375162<~~/~~ref~~><~~references group="xtra"~~/>

[[Category: Sulfolobus virus ragged hills]]

[[Category: Lawrence, C M.]]

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@@ Line 1: / Line 1: @@
-[[Image:2w8m.png|left|200px]]
+==STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.==
+<StructureSection load='2w8m' size='340' side='right' caption='[[2w8m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2w8m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W8M FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w8m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w8m RCSB], [http://www.ebi.ac.uk/pdbsum/2w8m PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Structural studies have made significant contributions to our understanding of Sulfolobus spindle-shaped viruses (Fuselloviridae), an important model system for archaeal viruses. Continuing these efforts, we report the structure of D212 from Sulfolobus spindle-shaped virus Ragged Hills. The overall fold and conservation of active site residues place D212 in the PD-(D/E)XK nuclease superfamily. The greatest structural similarity is found to the archaeal Holliday junction cleavage enzymes, strongly suggesting a role in DNA replication, repair, or recombination. Other roles associated with nuclease activity are also considered.
-{{STRUCTURE_2w8m|  PDB=2w8m  |  SCENE=  }}
+The crystal structure of D212 from sulfolobus spindle-shaped virus ragged hills reveals a new member of the PD-(D/E)XK nuclease superfamily.,Menon SK, Eilers BJ, Young MJ, Lawrence CM J Virol. 2010 Jun;84(12):5890-7. Epub 2010 Apr 7. PMID:20375162<ref>PMID:20375162</ref>
-===STRUCTURE OF D212, A NUCLEASE FROM A FUSSELOVIRUS.===
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-{{ABSTRACT_PUBMED_20375162}}
+== References ==
+<references/>
-==About this Structure==
+__TOC__
-[[2w8m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_ragged_hills Sulfolobus virus ragged hills]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8M OCA].
+</StructureSection>
-==Reference==
-<ref group="xtra">PMID:020375162</ref><references group="xtra"/>
 [[Category: Sulfolobus virus ragged hills]]
 [[Category: Lawrence, C M.]]