1kbo: Difference between revisions

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[[Image:1kbo.jpg|left|200px]]<br /><applet load="1kbo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kbo.jpg|left|200px]]
caption="1kbo, resolution 2.30&Aring;" />
 
'''Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340)'''<br />
{{Structure
|PDB= 1kbo |SIZE=350|CAPTION= <scene name='initialview01'>1kbo</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=340:5-METHOXY-1,2-DIMETHYL-3-(PHENOXYMETHYL)INDOLE-4,7-DIONE'>340</scene> and <scene name='pdbligand=FAD:FLAVIN-ADENINE DINUCLEOTIDE'>FAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2]
|GENE=
}}
 
'''Complex of Human recombinant NAD(P)H:Quinone Oxide reductase type 1 with 5-methoxy-1,2-dimethyl-3-(phenoxymethyl)indole-4,7-dione (ES1340)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KBO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=340:'>340</scene> and <scene name='pdbligand=FAD:'>FAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/NAD(P)H_dehydrogenase_(quinone) NAD(P)H dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.2 1.6.5.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KBO OCA].  
1KBO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KBO OCA].  


==Reference==
==Reference==
Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches., Winski SL, Faig M, Bianchet MA, Siegel D, Swann E, Fung K, Duncan MW, Moody CJ, Amzel LM, Ross D, Biochemistry. 2001 Dec 18;40(50):15135-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11735396 11735396]
Characterization of a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1 by biochemical, X-ray crystallographic, and mass spectrometric approaches., Winski SL, Faig M, Bianchet MA, Siegel D, Swann E, Fung K, Duncan MW, Moody CJ, Amzel LM, Ross D, Biochemistry. 2001 Dec 18;40(50):15135-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11735396 11735396]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: NAD(P)H dehydrogenase (quinone)]]
[[Category: NAD(P)H dehydrogenase (quinone)]]
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[[Category: prodrug-enzyme complex]]
[[Category: prodrug-enzyme complex]]


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