1ke0: Difference between revisions

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[[Image:1ke0.gif|left|200px]]<br /><applet load="1ke0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ke0.gif|left|200px]]
caption="1ke0, resolution 2.30&Aring;" />
 
'''X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-(carboxyvin-2-yl)phenylboronic acid'''<br />
{{Structure
|PDB= 1ke0 |SIZE=350|CAPTION= <scene name='initialview01'>1ke0</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=CVB:4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID'>CVB</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE= K12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-(carboxyvin-2-yl)phenylboronic acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KE0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=CVB:'>CVB</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KE0 OCA].  
1KE0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KE0 OCA].  


==Reference==
==Reference==
Structure-based approach for binding site identification on AmpC beta-lactamase., Powers RA, Shoichet BK, J Med Chem. 2002 Jul 18;45(15):3222-34. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12109906 12109906]
Structure-based approach for binding site identification on AmpC beta-lactamase., Powers RA, Shoichet BK, J Med Chem. 2002 Jul 18;45(15):3222-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12109906 12109906]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: serine hydrolase]]
[[Category: serine hydrolase]]


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