3ipi: Difference between revisions

Line 1:

~~{{STRUCTURE_3ipi| PDB=3ipi | SCENE= }}~~

==Crystal Structure of a Geranyltranstransferase from the Methanosarcina mazei==

===Crystal Structure of a Geranyltranstransferase from the Methanosarcina mazei===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[3ipi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IPI FirstGlance]. <br>

[[~~http://www.uniprot.org/uniprot/Q8PYS1_METMA Q8PYS1_METMA~~]] ~~Involved in biosynthesis of the polyprenyl side-chain of methanophenazine~~, an electron carrier utilized for methanogenesis. Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylfarnesyl diphosphate (GFPP). It prefers geranylgeranyl diphosphate (GGPP) and farnesyl diphosphate (FPP) as allylic substrate.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>

<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

==~~About this Structure~~==

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MM_0789 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])</td></tr>

[[3ipi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPI OCA].

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ipi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ipi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ipi RCSB], [http://www.ebi.ac.uk/pdbsum/3ipi PDBsum]</span></td></tr>

</table>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/3ipi_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

__TOC__

</StructureSection>

[[Category: Methanosarcina mazei]]

[[Category: Brown, A.]]

[[Category: Brown, A]]

[[Category: Burley, S K.]]

[[Category: Burley, S K]]

[[Category: Kumaran, D.]]

[[Category: Kumaran, D]]

[[Category: Mohammed, M B.]]

[[Category: Mohammed, M B]]

[[Category: ~~NYSGXRC, New York SGX Research Center for~~ Structural ~~Genomics.~~]]

[[Category: Structural genomic]]

[[Category: Swaminathan, S~~.]]~~

[[Category: Swaminathan, S]]

~~[[Category: 11257e~~]]

[[Category: Geranyltranstransferase]]

[[Category: Helical bundle]]

[[Category: Isoprene biosynthesis]]

[[Category: New ~~york sgx research center~~ for ~~structural genomic]]~~

[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]

~~[[Category: Nysgxrc]]~~

~~[[Category:~~ Structural ~~genomic~~]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3ipi|  PDB=3ipi  |  SCENE=  }}
+==Crystal Structure of a Geranyltranstransferase from the Methanosarcina mazei==
-===Crystal Structure of a Geranyltranstransferase from the Methanosarcina mazei===
+<StructureSection load='3ipi' size='340' side='right' caption='[[3ipi]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3ipi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IPI FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/Q8PYS1_METMA Q8PYS1_METMA]] Involved in biosynthesis of the polyprenyl side-chain of methanophenazine, an electron carrier utilized for methanogenesis. Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylfarnesyl diphosphate (GFPP). It prefers geranylgeranyl diphosphate (GGPP) and farnesyl diphosphate (FPP) as allylic substrate.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MM_0789 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])</td></tr>
-[[3ipi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPI OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ipi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ipi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ipi RCSB], [http://www.ebi.ac.uk/pdbsum/3ipi PDBsum]</span></td></tr>
+</table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/3ipi_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
 [[Category: Methanosarcina mazei]]
-[[Category: Brown, A.]]
+[[Category: Brown, A]]
-[[Category: Burley, S K.]]
+[[Category: Burley, S K]]
-[[Category: Kumaran, D.]]
+[[Category: Kumaran, D]]
-[[Category: Mohammed, M B.]]
+[[Category: Mohammed, M B]]
-[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
+[[Category: Structural genomic]]
-[[Category: Swaminathan, S.]]
+[[Category: Swaminathan, S]]
-[[Category: 11257e]]
 [[Category: Geranyltranstransferase]]
 [[Category: Helical bundle]]
 [[Category: Isoprene biosynthesis]]
-[[Category: New york sgx research center for structural genomic]]
+[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
-[[Category: Nysgxrc]]
-[[Category: Structural genomic]]
 [[Category: Transferase]]