1kr2: Difference between revisions

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[[Image:1kr2.jpg|left|200px]]<br /><applet load="1kr2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kr2.jpg|left|200px]]
caption="1kr2, resolution 2.30&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD)'''<br />
{{Structure
|PDB= 1kr2 |SIZE=350|CAPTION= <scene name='initialview01'>1kr2</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TAD:BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE'>TAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Nicotinamide-nucleotide_adenylyltransferase Nicotinamide-nucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.1 2.7.7.1]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KR2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TAD:'>TAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Nicotinamide-nucleotide_adenylyltransferase Nicotinamide-nucleotide adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.1 2.7.7.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KR2 OCA].  
1KR2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KR2 OCA].  


==Reference==
==Reference==
Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin., Zhou T, Kurnasov O, Tomchick DR, Binns DD, Grishin NV, Marquez VE, Osterman AL, Zhang H, J Biol Chem. 2002 Apr 12;277(15):13148-54. Epub 2002 Jan 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11788603 11788603]
Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin., Zhou T, Kurnasov O, Tomchick DR, Binns DD, Grishin NV, Marquez VE, Osterman AL, Zhang H, J Biol Chem. 2002 Apr 12;277(15):13148-54. Epub 2002 Jan 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11788603 11788603]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Nicotinamide-nucleotide adenylyltransferase]]
[[Category: Nicotinamide-nucleotide adenylyltransferase]]
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[[Category: nucleotidyltransferase superfamily]]
[[Category: nucleotidyltransferase superfamily]]


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