1kzn: Difference between revisions

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[[Image:1kzn.gif|left|200px]]<br /><applet load="1kzn" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kzn.gif|left|200px]]
caption="1kzn, resolution 2.30&Aring;" />
 
'''Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin'''<br />
{{Structure
|PDB= 1kzn |SIZE=350|CAPTION= <scene name='initialview01'>1kzn</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CBN:CLOROBIOCIN'>CBN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3]
|GENE=
}}
 
'''Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KZN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CBN:'>CBN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZN OCA].  
1KZN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZN OCA].  


==Reference==
==Reference==
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose., Lafitte D, Lamour V, Tsvetkov PO, Makarov AA, Klich M, Deprez P, Moras D, Briand C, Gilli R, Biochemistry. 2002 Jun 11;41(23):7217-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12044152 12044152]
DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose., Lafitte D, Lamour V, Tsvetkov PO, Makarov AA, Klich M, Deprez P, Moras D, Briand C, Gilli R, Biochemistry. 2002 Jun 11;41(23):7217-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12044152 12044152]
[[Category: DNA topoisomerase (ATP-hydrolyzing)]]
[[Category: DNA topoisomerase (ATP-hydrolyzing)]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: topoisomerase]]
[[Category: topoisomerase]]


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