4gd7: Difference between revisions

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{{STRUCTURE_4gd7| PDB=4gd7 | SCENE= }}
==Wild-Type Human Thymidylate Synthase with bound Purpurogallin==
===Wild-Type Human Thymidylate Synthase with bound Purpurogallin===
<StructureSection load='4gd7' size='340' side='right' caption='[[4gd7]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GD7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TIY:2,3,4,6-TETRAHYDROXY-5H-BENZO[7]ANNULEN-5-ONE'>TIY</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ehi|3ehi]], [[4g2o|4g2o]], [[4g6w|4g6w]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tys, ts, ok/sw-cl.29 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gd7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gd7 RCSB], [http://www.ebi.ac.uk/pdbsum/4gd7 PDBsum]</span></td></tr>
</table>


==Function==
==See Also==
[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref> 
*[[Thymidylate synthase|Thymidylate synthase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4gd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA].
[[Category: Human]]
 
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
[[Category: Celeste, L R.]]
[[Category: Celeste, L R]]
[[Category: Lebioda, L.]]
[[Category: Lebioda, L]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Transferase-transferase inhibitor complex]]
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