2wot: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==ALK5 IN COMPLEX WITH 4-((5,6- | ==ALK5 IN COMPLEX WITH 4-((5,6-dimethyl-2-(2-pyridyl)-3-pyridyl)oxy)-N-(3,4,5-trimethoxyphenyl)pyridin-2-amine== | ||
<StructureSection load='2wot' size='340' side='right' caption='[[2wot]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='2wot' size='340' side='right' caption='[[2wot]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2wot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WOT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WOT FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZG:4-[(5,6-DIMETHYL-2,2-BIPYRIDIN-3-YL)OXY]-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE'>ZZG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZZG:4-[(5,6-DIMETHYL-2,2-BIPYRIDIN-3-YL)OXY]-N-(3,4,5-TRIMETHOXYPHENYL)PYRIDIN-2-AMINE'>ZZG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wou|2wou]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1py5|1py5]], [[1ias|1ias]], [[1b6c|1b6c]], [[1vjy|1vjy]], [[1rw8|1rw8]], [[2wou|2wou]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wot RCSB], [http://www.ebi.ac.uk/pdbsum/2wot PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wot FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wot OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wot RCSB], [http://www.ebi.ac.uk/pdbsum/2wot PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 30: | Line 30: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Receptor protein serine/threonine kinase]] | [[Category: Receptor protein serine/threonine kinase]] | ||
[[Category: Debreczeni, J E | [[Category: Debreczeni, J E]] | ||
[[Category: Dishington, A P | [[Category: Dishington, A P]] | ||
[[Category: Finlay, R | [[Category: Finlay, R]] | ||
[[Category: Gingell, H J | [[Category: Gingell, H J]] | ||
[[Category: Goldberg, F W | [[Category: Goldberg, F W]] | ||
[[Category: Norman, R A | [[Category: Norman, R A]] | ||
[[Category: Powell, S J | [[Category: Powell, S J]] | ||
[[Category: Roberts, A L | [[Category: Roberts, A L]] | ||
[[Category: Roberts, N J | [[Category: Roberts, N J]] | ||
[[Category: Ward, R A | [[Category: Ward, R A]] | ||
[[Category: Wickson, K F | [[Category: Wickson, K F]] | ||
[[Category: Alk5]] | [[Category: Alk5]] | ||
[[Category: Aortic aneurysm]] | [[Category: Aortic aneurysm]] | ||
Revision as of 10:45, 19 November 2014
ALK5 IN COMPLEX WITH 4-((5,6-dimethyl-2-(2-pyridyl)-3-pyridyl)oxy)-N-(3,4,5-trimethoxyphenyl)pyridin-2-amine
| ||||||||||||
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Receptor protein serine/threonine kinase
- Debreczeni, J E
- Dishington, A P
- Finlay, R
- Gingell, H J
- Goldberg, F W
- Norman, R A
- Powell, S J
- Roberts, A L
- Roberts, N J
- Ward, R A
- Wickson, K F
- Alk5
- Aortic aneurysm
- Atp-binding
- Craniosynostosis
- Disease mutation
- Disulfide bond
- Glycoprotein
- Kinase
- Kinase inhibitor
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Receptor
- Serine/threonine-protein kinase
- Tgf beta type i receptor
- Transferase
- Transmembrane
