4p5x: Difference between revisions
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''' | ==Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the calcium-bound state== | ||
<StructureSection load='4p5x' size='340' side='right' caption='[[4p5x]], [[Resolution|resolution]] 2.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4p5x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P5X FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5w|4p5w]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p5x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p5x RCSB], [http://www.ebi.ac.uk/pdbsum/4p5x PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Epileptic encephalopathy with global cerebral demyelination. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.<ref>PMID:11566871</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Kunji, E R.S]] | |||
[[Category: Ruprecht, J J]] | |||
[[Category: Thangaratnarajah, C]] | |||
[[Category: Calcium binding protein]] | |||
[[Category: Ef hand]] | |||
[[Category: Mitochondrial carrier]] | |||
[[Category: Regulatory-domain]] | |||
Revision as of 08:11, 26 November 2014
Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the calcium-bound state
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