4p60: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state==

~~The entry~~ 4p60 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4p60]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P60 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P60 FirstGlance].

~~Authors~~: ~~Thangaratnarajah~~, C., ~~Ruprecht~~, J.J.~~, Kunji, E~~.R.S.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4p5x|4p5x]]</td></tr>

~~Description~~: ~~Structure of~~ the N-~~terminal domain~~ of the ~~human~~ mitochondrial ~~aspartate/glutamate carrier Aralar~~ in the ~~apo state~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p60 RCSB], [http://www.ebi.ac.uk/pdbsum/4p60 PDBsum]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Epileptic encephalopathy with global cerebral demyelination. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.<ref>PMID:11566871</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Kunji, E R.S]]

[[Category: Ruprecht, J J]]

[[Category: Thangaratnarajah, C]]

[[Category: Transport protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state==
+<StructureSection load='4p60' size='340' side='right' caption='[[4p60]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-The entry 4p60 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4p60]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P60 FirstGlance]. <br>
-Authors: Thangaratnarajah, C., Ruprecht, J.J., Kunji, E.R.S.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p5x|4p5x]]</td></tr>
-Description: Structure of the N-terminal domain of the human mitochondrial aspartate/glutamate carrier Aralar in the apo state
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p60 RCSB], [http://www.ebi.ac.uk/pdbsum/4p60 PDBsum]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Epileptic encephalopathy with global cerebral demyelination. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/CMC1_HUMAN CMC1_HUMAN]] Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.<ref>PMID:11566871</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Kunji, E R.S]]
+[[Category: Ruprecht, J J]]
+[[Category: Thangaratnarajah, C]]
+[[Category: Transport protein]]