1m0o: Difference between revisions

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[[Image:1m0o.jpg|left|200px]]<br /><applet load="1m0o" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1m0o.jpg|left|200px]]
caption="1m0o, resolution 2.4&Aring;" />
 
'''Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate'''<br />
{{Structure
|PDB= 1m0o |SIZE=350|CAPTION= <scene name='initialview01'>1m0o</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=MPM:(1R)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]-1-METHYLPROPYLPHOSPHONIC ACID'>MPM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/2,2-dialkylglycine_decarboxylase_(pyruvate) 2,2-dialkylglycine decarboxylase (pyruvate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.64 4.1.1.64]
|GENE=
}}
 
'''Structure of Dialkylglycine Decarboxylase Complexed with 1-Amino-1-methylpropanephosphonate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1M0O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia] with <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=MPM:'>MPM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/2,2-dialkylglycine_decarboxylase_(pyruvate) 2,2-dialkylglycine decarboxylase (pyruvate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.64 4.1.1.64] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0O OCA].  
1M0O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Burkholderia_cepacia Burkholderia cepacia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M0O OCA].  


==Reference==
==Reference==
Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition., Liu W, Rogers CJ, Fisher AJ, Toney MD, Biochemistry. 2002 Oct 15;41(41):12320-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12369820 12369820]
Aminophosphonate inhibitors of dialkylglycine decarboxylase: structural basis for slow binding inhibition., Liu W, Rogers CJ, Fisher AJ, Toney MD, Biochemistry. 2002 Oct 15;41(41):12320-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12369820 12369820]
[[Category: 2,2-dialkylglycine decarboxylase (pyruvate)]]
[[Category: 2,2-dialkylglycine decarboxylase (pyruvate)]]
[[Category: Burkholderia cepacia]]
[[Category: Burkholderia cepacia]]
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[[Category: pyridoxal phosphate]]
[[Category: pyridoxal phosphate]]


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