Growth differentiation factor: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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===GDF-2===
*GDF-2


[[1zkz]] – hGDF – human  <br />
**[[1zkz]] – hGDF – human  <br />
[[4fao]] – hGDF + serine/threonine-protein kinase receptor + activin receptor<br />
**[[4fao]] – hGDF + serine/threonine-protein kinase receptor + activin receptor<br />


===GDF-5===
*GDF-5


[[2bhk]], [[1waq]] – hGDF  <br />
**[[2bhk]], [[1waq]] – hGDF  <br />
[[3evs]] – hGDF + bone morphogenetic receptor  <br />
**[[3evs]] – hGDF + bone morphogenetic receptor  <br />
[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor  <br />
**[[3qb4]] – hGDF (mutant) + bone morphogenetic receptor  <br />


===GDF-8===
*GDF-8


[[3hh2]] – mGDF + follistatin – mouse  <br />
**[[3hh2]] – mGDF + follistatin – mouse  <br />
[[3sek]] – mGDF + follistatin-related protein  <br />
**[[3sek]] – mGDF + follistatin-related protein  <br />
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:34, 26 November 2014

<StructureSection load='3evs' size='350' side='right' caption='Structure of growth differentiation factor GDF-5 (green) complex with bone morphogenetic receptor (pink) (PDB entry 3evs)' scene=>

Growth differentiation factor (GDF) are proteins which function in development.

  • GDF-2 maintains the response of cholinergic neurons to acetylcholine.
  • GDF-5 is expressed in the central nervous system and is involved in the development of joints and skeleton.
  • GDF-8 or myostatin, controls the growth of muscle tissue. For more details see Group:MUZIC:Myostatin.

3D structures of growth differentiation factor

Updated on 26-November-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky