Keithballard/sandbox: Difference between revisions

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 ==Structure of Class I cytosolic sHSP==
 <StructureSection load='1gme' size='340' side='right' caption='Caption for this structure' scene=''>
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+==Introduction==
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
+Small heat shock proteins (sHSPs) and related α-crystallins are virtually ubiquitous, ATP-independent molecular chaperones linked to diseases of protein misfolding. They comprise a conserved core α-crystallin domain (ACD) flanked by an evolutionarily variable N-terminal arm (NTA) and semi-conserved C-terminal extension. They are capable of binding up to an equal mass of unfolding protein, forming large, heterogeneous sHSP-substrate complexes that make substrate available to the ATP-dependent chaperones for refolding.
 == Function ==

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