Molecular Playground/IntegrinBeta1: Difference between revisions
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<Structure load='3VI4' size='350' frame='true' align='right' caption='Integrin Beta 1 Alpha 5' scene='60/609772/Integrinb1alpha5/1' /> | <Structure load='3VI4' size='350' frame='true' align='right' caption='Integrin Beta 1 Alpha 5' scene='60/609772/Integrinb1alpha5/1' /> | ||
==Structure== | ==Structure== | ||
Integrins are surface proteins that are comprised of an alpha subunit and a beta subunit to form a functional transmembrane structure. The subunits of the heterodimer each have small cytoplasmic domains for signal transduction within the cell. | Integrins are surface proteins that are comprised of an alpha subunit and a beta subunit to form a functional transmembrane structure. The subunits of the heterodimer each have small cytoplasmic domains for signal transduction within the cell. Different pairs of alpha and beta subunits uniquely bind to extracellular proteins. Integrins connect the extracellular environment to the inside of a cell to induce signaling within the cell. | ||
The protein structure on the right has the following color coding: Blue-Alpha 5 chain, Red-Beta 1 chain, Grey-SG/19 Fab fragment light chain, Green-SG/19 Fab fragment heavy chain. | The protein structure on the right has the following color coding: Blue-Alpha 5 chain, Red-Beta 1 chain, Grey-SG/19 Fab fragment light chain, Green-SG/19 Fab fragment heavy chain. | ||
