1m7p: Difference between revisions

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[[Image:1m7p.jpg|left|200px]]<br /><applet load="1m7p" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1m7p.jpg|left|200px]]
caption="1m7p, resolution 2.40&Aring;" />
 
'''Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P).'''<br />
{{Structure
|PDB= 1m7p |SIZE=350|CAPTION= <scene name='initialview01'>1m7p</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1]
|GENE= TPI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])
}}
 
'''Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P).'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1M7P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=G3H:'>G3H</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7P OCA].  
1M7P is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7P OCA].  


==Reference==
==Reference==
Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state., Parthasarathy S, Balaram H, Balaram P, Murthy MR, Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):1992-2000. Epub, 2002 Nov 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12454456 12454456]
Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state., Parthasarathy S, Balaram H, Balaram P, Murthy MR, Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):1992-2000. Epub, 2002 Nov 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12454456 12454456]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tim barrles; beta-alpha barrels; enzyme-inhibitor complex]]
[[Category: tim barrles; beta-alpha barrels; enzyme-inhibitor complex]]


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