1m9t: Difference between revisions

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[[Image:1m9t.jpg|left|200px]]<br /><applet load="1m9t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1m9t.jpg|left|200px]]
caption="1m9t, resolution 2.40&Aring;" />
 
'''Inducible Nitric Oxide Synthase with 3-Bromo-7-Nitroindazole bound'''<br />
{{Structure
|PDB= 1m9t |SIZE=350|CAPTION= <scene name='initialview01'>1m9t</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=INE:3-BROMO-7-NITROINDAZOLE'>INE</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Nitric-oxide_synthase Nitric-oxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39]
|GENE= iNOS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Inducible Nitric Oxide Synthase with 3-Bromo-7-Nitroindazole bound'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1M9T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=HEM:'>HEM</scene>, <scene name='pdbligand=H4B:'>H4B</scene>, <scene name='pdbligand=INE:'>INE</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Nitric-oxide_synthase Nitric-oxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.39 1.14.13.39] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M9T OCA].  
1M9T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M9T OCA].  


==Reference==
==Reference==
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency., Rosenfeld RJ, Garcin ED, Panda K, Andersson G, Aberg A, Wallace AV, Morris GM, Olson AJ, Stuehr DJ, Tainer JA, Getzoff ED, Biochemistry. 2002 Nov 26;41(47):13915-25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12437348 12437348]
Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency., Rosenfeld RJ, Garcin ED, Panda K, Andersson G, Aberg A, Wallace AV, Morris GM, Olson AJ, Stuehr DJ, Tainer JA, Getzoff ED, Biochemistry. 2002 Nov 26;41(47):13915-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12437348 12437348]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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