1me4: Difference between revisions
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[[Image:1me4.jpg|left|200px]] | [[Image:1me4.jpg|left|200px]] | ||
'''High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)''' | {{Structure | ||
|PDB= 1me4 |SIZE=350|CAPTION= <scene name='initialview01'>1me4</scene>, resolution 1.2Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=T10:[1-(1-BENZYL-3-HYDROXY-2-OXO-PROPYLCARBAMOYL)-2-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER'>T10</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''High Resolution Crystal Structure Analysis Of Cruzain non-covalently Bound To A Hydroxymethyl Ketone Inhibitor (I)''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1ME4 is a [ | 1ME4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ME4 OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain., Huang L, Brinen LS, Ellman JA, Bioorg Med Chem. 2003 Jan 2;11(1):21-9. PMID:[http:// | Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain., Huang L, Brinen LS, Ellman JA, Bioorg Med Chem. 2003 Jan 2;11(1):21-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12467703 12467703] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Trypanosoma cruzi]] | [[Category: Trypanosoma cruzi]] | ||
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[[Category: non-covalent inhibitor]] | [[Category: non-covalent inhibitor]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:42:27 2008'' | ||