Pre-mRNA-splicing factor: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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===Pre-mRNA-splicing factor 2===
*Pre-mRNA-splicing factor 2


[[3beg]] – hPrp residues 105-219 + Ser/Thr-protein kinase – human<BR />
**[[3beg]] – hPrp residues 105-219 + Ser/Thr-protein kinase – human<BR />
[[2o3d]] – hPrp P33 subunit
**[[2o3d]] – hPrp P33 subunit


===Pre-mRNA-splicing factor 3===
*Pre-mRNA-splicing factor 3


[[1x4q]] – hPrp PWI domain - NMR<BR />
**[[1x4q]] – hPrp PWI domain - NMR<BR />


===Pre-mRNA-splicing factor 3B===
*Pre-mRNA-splicing factor 3B


[[3lqv]], [[2f9d]], [[2f9j]] – hPrp residues 377-415 + pre-mRNA branch site protein 14<BR />
**[[3lqv]], [[2f9d]], [[2f9j]] – hPrp residues 377-415 + pre-mRNA branch site protein 14<BR />
[[2fho]] - hPrp residues 379-424 + spliceosomal protein P14 - NMR<BR />
**[[2fho]] - hPrp residues 379-424 + spliceosomal protein P14 - NMR<BR />
[[2do5]] – hPrp subunit 2 – NMR<BR />
**[[2do5]] – hPrp subunit 2 – NMR<BR />
[[1x5t]] - hPrp subunit 4 – NMR<BR />
**[[1x5t]] - hPrp subunit 4 – NMR<BR />
[[1x5u]] - hPrp subunit 4 RNA-binding domain – NMR<BR />
**[[1x5u]] - hPrp subunit 4 RNA-binding domain – NMR<BR />


===Pre-mRNA-splicing factor 8===
*Pre-mRNA-splicing factor 8


[[3sbt]], [[4ilh]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast<BR />
**[[3sbt]], [[4ilh]] – yPrp RNAseH like domain + A1 cistron-splicing factor AAR2 – yeast<BR />
[[4jk7]], [[4jk9]] - yPrp RNAseH like domain <br />
**[[4jk7]], [[4jk9]] - yPrp RNAseH like domain <br />
[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]]  - yPrp RNAseH like domain (mutant)<br />
**[[4ilj]], [[4jk8]], [[4jka]], [[4jkb]], [[4jkc]], [[4jkd]], [[4jke]], [[4jkf]], [[4jkg]], [[4jkh]]  - yPrp RNAseH like domain (mutant)<br />
[[3e66]] – yPrp β-finger domain<BR />
**[[3e66]] – yPrp β-finger domain<BR />
[[3e9o]], [[3e9p]] - yPrp RNA-binding domain<BR />
**[[3e9o]], [[3e9p]] - yPrp RNA-binding domain<BR />
[[2p87]], [[2og4]], [[3sbg]] - yPrp C terminal<BR />
**[[2p87]], [[2og4]], [[3sbg]] - yPrp C terminal<BR />
[[3zef]], [[4i43]] – yPrp + A1 cistron-splicing factor AAR2<br />
**[[3zef]], [[4i43]] – yPrp + A1 cistron-splicing factor AAR2<br />
[[4bgd]] – yPrp JAB1/MPN domain + pre-mRNA-splicing helicase BRR2<br />
**[[4bgd]] – yPrp JAB1/MPN domain + pre-mRNA-splicing helicase BRR2<br />
[[4kit]] – yPrp JAB1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br />
**[[4kit]] – yPrp JAB1/MPN domain + U5 small nuclear ribonucleoprotein helicase <br />
[[4ilg]] – yPrp JAB1/MPN+RNAseH domains + A1 cistron-splicing factor AAR2 <br />
**[[4ilg]] – yPrp JAB1/MPN+RNAseH domains + A1 cistron-splicing factor AAR2 <br />
[[4bgd]] – yPrp JAB1/MPN+RNAseH domains + A1 cistron-splicing factor AAR2 + pre-mRNA-splicing helicase BRR2<br />
**[[4bgd]] – yPrp JAB1/MPN+RNAseH domains + A1 cistron-splicing factor AAR2 + pre-mRNA-splicing helicase BRR2<br />
[[3lru]] – hPrp residues 1831-1990<BR />
**[[3lru]] – hPrp residues 1831-1990<BR />
[[3e9l]] – hPrp endonuclease domain<BR />
**[[3e9l]] – hPrp endonuclease domain<BR />
[[3enb]] - hPrp core domain IV<BR />
**[[3enb]] - hPrp core domain IV<BR />
[[2p8r]] – Prp C terminal (mutant) – ''Caenorhabditis elegans''
**[[2p8r]] – Prp C terminal (mutant) – ''Caenorhabditis elegans''


===Pre-mRNA-splicing factor 9===
*Pre-mRNA-splicing factor 9


[[4dgw]] – yPrp + Prp 21 + Prp 11
**[[4dgw]] – yPrp + Prp 21 + Prp 11


===Pre-mRNA-splicing factor 11===
*Pre-mRNA-splicing factor 11


[[4dgw]] – yPrp + Prp 21 + Prp 9
**[[4dgw]] – yPrp + Prp 21 + Prp 9


===Pre-mRNA-splicing factor 18===
*Pre-mRNA-splicing factor 18


[[2dk4]] – hPrp splicing factor motif domain - NMR<BR />
**[[2dk4]] – hPrp splicing factor motif domain - NMR<BR />


===Pre-mRNA-splicing factor 19===
*Pre-mRNA-splicing factor 19


[[3lrv]] – yPrp WD40 domain<BR />
**[[3lrv]] – yPrp WD40 domain<BR />
[[2bay]] – yPrp U-box<BR />
**[[2bay]] – yPrp U-box<BR />
[[1n87]] - yPrp U-box - NMR<BR />
**[[1n87]] - yPrp U-box - NMR<BR />


===Pre-mRNA-splicing factor 20===
*Pre-mRNA-splicing factor 20


[[2i2y]] – Prp RNA-binding domain + RNA – ''Streptococcus'' – NMR<BR />
**[[2i2y]] – Prp RNA-binding domain + RNA – ''Streptococcus'' – NMR<BR />
[[2i38]] - hPrp RNA-binding domain (mutant) – NMR<BR />
**[[2i38]] - hPrp RNA-binding domain (mutant) – NMR<BR />


===Pre-mRNA-splicing factor 21===
*Pre-mRNA-splicing factor 21


[[4dgw]] – yPrp + Prp 9 + Prp 11
**[[4dgw]] – yPrp + Prp 9 + Prp 11


===snRNA-associated-splicing factor 24===
*snRNA-associated-splicing factor 24


[[2l9w]] – yPrp C terminal – NMR<BR />
**[[2l9w]] – yPrp C terminal – NMR<BR />
[[2kh9]] – yPrp residues 115-197 + RNA – NMR<BR />
**[[2kh9]] – yPrp residues 115-197 + RNA – NMR<BR />
[[2go9]] – yPrp RNA-binding  domains – NMR<BR />
**[[2go9]] – yPrp RNA-binding  domains – NMR<BR />
[[2ghp]] - yPrp RNA-binding  domains
**[[2ghp]] - yPrp RNA-binding  domains


===Pre-mRNA-splicing factor 31===
*Pre-mRNA-splicing factor 31


[[2ozb]] – hPrp + RNA + tri-snRNP <br />
**[[2ozb]] – hPrp + RNA + tri-snRNP <br />
[[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br />
**[[3siu]], [[3siv]] – hPrp + NHP2-like protein + snRNP <br />


===Pre-mRNA-splicing factor 40===
*Pre-mRNA-splicing factor 40


[[1o6w]] – yPrp WW domain – yeast - NMR<br />
**[[1o6w]] – yPrp WW domain – yeast - NMR<br />
[[2b7e]] – yPrp FF1 domain - NMR<br />
**[[2b7e]] – yPrp FF1 domain - NMR<br />
[[2kfd]] – yPrp FF4 domain - NMR<br />
**[[2kfd]] – yPrp FF4 domain - NMR<br />


===Pre-mRNA-splicing factor 43P===
*Pre-mRNA-splicing factor 43P


[[2xau]], [[3kx2]] – yPrp + ADP
**[[2xau]], [[3kx2]] – yPrp + ADP


===Pre-mRNA-splicing factor cwc2===
*Pre-mRNA-splicing factor cwc2


[[3tp2]], [[3u1l]], [[3u1m]] – yPrp <br />
**[[3tp2]], [[3u1l]], [[3u1m]] – yPrp <br />


===Pre-mRNA-splicing factor RBM22===
*Pre-mRNA-splicing factor RBM22


[[2ytc]] – yPrp RNA-binding domain - NMR<BR />
**[[2ytc]] – yPrp RNA-binding domain - NMR<BR />


*Pre-mRNA-splicing factor RDS3


===Pre-mRNA-splicing factor RDS3===
**[[2k0a]] – yPrp - NMR<BR />


[[2k0a]] – yPrp - NMR<BR />
*Pre-mRNA-splicing factor URN1
 
===Pre-mRNA-splicing factor URN1===
 
[[2juc]] – yPrp FF domain - NMR<BR />


**[[2juc]] – yPrp FF domain - NMR<BR />
}}





Revision as of 10:17, 4 December 2014

Template:STRUCTURE 3e9l

Pre-mRNA-splicing factors (Prp) are the proteins which associate with mRNA at its various splicing sites to produce alternative splicing. For details on pre-mRNA-splicing factors see

3D Structures of pre-mRNA splicing factors

Updated on 04-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman