1mmj: Difference between revisions

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[[Image:1mmj.gif|left|200px]]<br /><applet load="1mmj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1mmj.gif|left|200px]]
caption="1mmj, resolution 2.2&Aring;" />
 
'''Porcine pancreatic elastase complexed with a potent peptidyl inhibitor, FR136706'''<br />
{{Structure
|PDB= 1mmj |SIZE=350|CAPTION= <scene name='initialview01'>1mmj</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=FR1:2-[4-[[(S)-1-[[(S)-2-[[(RS)-3,3,3-TRIFLUORO-1-ISOPROPYL-2-OXOPROPYL]AMINOCARBONYL]PYRROLIDIN-1-YL-]CARBONYL]-2-METHYLPROPYL]AMINOCARBONYL]BENZOYLAMINO]ACETIC ACID'>FR1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36]
|GENE=
}}
 
'''Porcine pancreatic elastase complexed with a potent peptidyl inhibitor, FR136706'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1MMJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=FR1:'>FR1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMJ OCA].  
1MMJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MMJ OCA].  


==Reference==
==Reference==
True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor., Kinoshita T, Nakanishi I, Sato A, Tada T, Bioorg Med Chem Lett. 2003 Jan 6;13(1):21-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12467609 12467609]
True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor., Kinoshita T, Nakanishi I, Sato A, Tada T, Bioorg Med Chem Lett. 2003 Jan 6;13(1):21-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12467609 12467609]
[[Category: Pancreatic elastase]]
[[Category: Pancreatic elastase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: chymotrypsin family]]
[[Category: chymotrypsin family]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:56:41 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:45:22 2008''
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