1muu: Difference between revisions

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[[Image:1muu.gif|left|200px]]<br /><applet load="1muu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1muu.gif|left|200px]]
caption="1muu, resolution 2.0&Aring;" />
 
'''2.0 A crystal structure of GDP-mannose dehydrogenase'''<br />
{{Structure
|PDB= 1muu |SIZE=350|CAPTION= <scene name='initialview01'>1muu</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SUC:SUCROSE'>SUC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=GDX:GUANOSINE 5'-(TRIHYDROGEN DIPHOSPHATE), P'-D-MANNOPYRANOSYL ESTER'>GDX</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GDP-mannose_6-dehydrogenase GDP-mannose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.132 1.1.1.132]
|GENE= algD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
}}
 
'''2.0 A crystal structure of GDP-mannose dehydrogenase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1MUU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] with <scene name='pdbligand=SUC:'>SUC</scene>, <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=GDX:'>GDX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GDP-mannose_6-dehydrogenase GDP-mannose 6-dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.132 1.1.1.132] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUU OCA].  
1MUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUU OCA].  


==Reference==
==Reference==
Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa., Snook CF, Tipton PA, Beamer LJ, Biochemistry. 2003 Apr 29;42(16):4658-68. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12705829 12705829]
Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa., Snook CF, Tipton PA, Beamer LJ, Biochemistry. 2003 Apr 29;42(16):4658-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12705829 12705829]
[[Category: GDP-mannose 6-dehydrogenase]]
[[Category: GDP-mannose 6-dehydrogenase]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: rossman fold; domain-swapped dimer; enzyme complex with cofactor and product]]
[[Category: rossman fold; domain-swapped dimer; enzyme complex with cofactor and product]]


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