Emily Ellis/Sandbox: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 68: Line 68:
==Medical Uses==
==Medical Uses==
The drug Salbutamol is an asthma drug used to treat chronic bronchitis, COPD (chronic obstructive pulmonary disorder), and exercise-induced asthma.  It is also known as Albuterol, Levalbuterol, and Proventil.  It is generally an oral inhaler that is used for prevention and treatment of the symptoms that accompany the conditions mentioned before.   
The drug Salbutamol is an asthma drug used to treat chronic bronchitis, COPD (chronic obstructive pulmonary disorder), and exercise-induced asthma.  It is also known as Albuterol, Levalbuterol, and Proventil.  It is generally an oral inhaler that is used for prevention and treatment of the symptoms that accompany the conditions mentioned before.   


The drug itself is a racemic mixture, or combination of both the S-isomer (the mirror image) and the R-isomer (the drug).  The R-isomer is 150 times more likely to bond with the beta2-adrenergic receptor than the S-isomer, but it is much less expensive for the drug companies to produce both isomers when creating the drugs.  The beta2-adrenergic receptors (usually pulmonary) are 29 times more receptive to the Salbutamol than the beta1-adrenergic receptors, which are usually found in the heart.  
The drug itself is a racemic mixture, or combination of both the S-isomer (the mirror image) and the R-isomer (the drug).  The R-isomer is 150 times more likely to bond with the beta2-adrenergic receptor than the S-isomer, but it is much less expensive for the drug companies to produce both isomers when creating the drugs.  The beta2-adrenergic receptors (usually pulmonary) are 29 times more receptive to the Salbutamol than the beta1-adrenergic receptors, which are usually found in the heart.  


Some common brand names for the drug are: Aerolin, ProAir, and Ventolin.   
Some common brand names for the drug are: Aerolin, ProAir, and Ventolin.   


<br>
<br>