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[[Image:3n56.png|left|200px]]
==Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP)==
 
<StructureSection load='3n56' size='340' side='right' caption='[[3n56]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
{{STRUCTURE_3n56|  PDB=3n56  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3n56]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N56 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N56 FirstGlance]. <br>
===Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP)===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2g47|2g47]], [[2wby|2wby]], [[3cww|3cww]], [[3h44|3h44]], [[3e4z|3e4z]], [[1yk1|1yk1]], [[3n57|3n57]]</td></tr>
{{ABSTRACT_PUBMED_021098034}}
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HCG_1810909, IDE, RP11-366I13.1-001 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), NPPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Insulysin Insulysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.56 3.4.24.56] </span></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n56 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n56 RCSB], [http://www.ebi.ac.uk/pdbsum/3n56 PDBsum]</span></td></tr>
[[3n56]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N56 OCA].  
</table>


==See Also==
==See Also==
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]
*[[Insulin-Degrading Enzyme|Insulin-Degrading Enzyme]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021098034</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Insulysin]]
[[Category: Insulysin]]
[[Category: Funke, T.]]
[[Category: Funke, T]]
[[Category: Guo, Q.]]
[[Category: Guo, Q]]
[[Category: Tang, W J.]]
[[Category: Tang, W J]]
[[Category: A-beta degrading enzyme]]
[[Category: A-beta degrading enzyme]]
[[Category: Cardiac]]
[[Category: Cardiac]]
Line 33: Line 32:
[[Category: Insulin]]
[[Category: Insulin]]
[[Category: Insulinase]]
[[Category: Insulinase]]
[[Category: Insulysin]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Metalloprotease]]

Revision as of 08:28, 9 December 2014

Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human B-type natriuretic peptide (BNP)

3n56, resolution 3.10Å

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