1mx9: Difference between revisions

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[[Image:1mx9.gif|left|200px]]~~<br /><applet load~~="1mx9~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1mx9.gif|left|200px]]

~~caption="~~1mx9, resolution 2.90Å" />

'''Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue'''~~<br />~~

{{Structure

|PDB= 1mx9 |SIZE=350|CAPTION= <scene name='initialview01'>1mx9</scene>, resolution 2.90Å

|SITE=

|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=NLX:(5A,17R)-4,5-EPOXY-3,14-DIHYDROXY-17-METHYL-6-OXO-17-(2-PROPENYL)-MORPHINANIUM'>NLX</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1]

|GENE=

}}

'''Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue'''

==Overview==

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==About this Structure==

1MX9 is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=NLX:'>NLX</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. ~~Active as [http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX9 OCA].

1MX9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX9 OCA].

==Reference==

Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme., Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR, Nat Struct Biol. 2003 May;10(5):349-56. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~12679808 12679808]

Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme., Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR, Nat Struct Biol. 2003 May;10(5):349-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12679808 12679808]

[[Category: Carboxylesterase]]

[[Category: Homo sapiens]]

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[[Category: hydrolase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 13~~:59:59 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:49:32 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1mx9.gif|left|200px]]<br /><applet load="1mx9" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1mx9.gif|left|200px]]
-caption="1mx9, resolution 2.90&Aring;" />
-'''Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue'''<br />
+ {{Structure
+|PDB= 1mx9 |SIZE=350|CAPTION= <scene name='initialview01'>1mx9</scene>, resolution 2.90&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=NLX:(5A,17R)-4,5-EPOXY-3,14-DIHYDROXY-17-METHYL-6-OXO-17-(2-PROPENYL)-MORPHINANIUM'>NLX</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1]
+|GENE=
+}}
+'''Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-MX9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=NLX:'>NLX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carboxylesterase Carboxylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.1 3.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX9 OCA].
+MX9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MX9 OCA].
 ==Reference==
-Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme., Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR, Nat Struct Biol. 2003 May;10(5):349-56. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12679808 12679808]
+Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme., Bencharit S, Morton CL, Xue Y, Potter PM, Redinbo MR, Nat Struct Biol. 2003 May;10(5):349-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12679808 12679808]
 [[Category: Carboxylesterase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: hydrolase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:59:59 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:49:32 2008''