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[[Image:3m49.png|left|200px]]
==Crystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracis==
 
<StructureSection load='3m49' size='340' side='right' caption='[[3m49]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
{{STRUCTURE_3m49|  PDB=3m49  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3m49]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3k95 3k95]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M49 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M49 FirstGlance]. <br>
===Crystal Structure of Transketolase Complexed with Thiamine Diphosphate from Bacillus anthracis===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TDP:THIAMIN+DIPHOSPHATE'>TDP</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hyl|3hyl]], [[3k95|3k95]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAS3470, BA_3744, GBAA3744, GBAA_3744, tkt-2, tkt2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
[[3m49]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3k95 3k95]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M49 OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m49 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m49 RCSB], [http://www.ebi.ac.uk/pdbsum/3m49 PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/3m49_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Transketolase|Transketolase]]
*[[Transketolase|Transketolase]]
__TOC__
</StructureSection>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Transketolase]]
[[Category: Transketolase]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Kim, Y.]]
[[Category: Kim, Y]]
[[Category: Kwon, K.]]
[[Category: Kwon, K]]
[[Category: Maltseva, N.]]
[[Category: Maltseva, N]]
[[Category: Alpha-beta-alpha sandwich]]
[[Category: Alpha-beta-alpha sandwich]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Structural genomic]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Structural genomic]]
[[Category: Transferase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3m49"