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[[Image:3mdz.png|left|200px]]
==Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7==
 
<StructureSection load='3mdz' size='340' side='right' caption='[[3mdz]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
{{STRUCTURE_3mdz|  PDB=3mdz  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3mdz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MDZ FirstGlance]. <br>
===Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EZL:6-ETHOXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE'>EZL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3caj|3caj]]</td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
[[3mdz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MDZ OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mdz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mdz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mdz RCSB], [http://www.ebi.ac.uk/pdbsum/3mdz PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/3mdz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Carbonic anhydrase|Carbonic anhydrase]]
*[[Carbonic anhydrase|Carbonic anhydrase]]
__TOC__
</StructureSection>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Bray, J.]]
[[Category: Bray, J]]
[[Category: Carpenter, E P.]]
[[Category: Carpenter, E P]]
[[Category: Chaikuad, A.]]
[[Category: Chaikuad, A]]
[[Category: Delft, F von.]]
[[Category: Delft, F von]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Kim, J.]]
[[Category: Kim, J]]
[[Category: Krojer, T.]]
[[Category: Krojer, T]]
[[Category: Muniz, J.]]
[[Category: Muniz, J]]
[[Category: Oppermann, U.]]
[[Category: Oppermann, U]]
[[Category: Pilka, E.]]
[[Category: Pilka, E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Shafqat, N.]]
[[Category: Shafqat, N]]
[[Category: Ugochukwu, E.]]
[[Category: Ugochukwu, E]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Yue, W W.]]
[[Category: Yue, W W]]
[[Category: Ca7]]
[[Category: Ca7]]
[[Category: Carbonic anhydrase vii]]
[[Category: Carbonic anhydrase vii]]
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[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]

Revision as of 09:09, 9 December 2014

Crystal Structure of Human Carbonic Anhydrase VII [isoform 1], CA7

3mdz, resolution 2.32Å

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