1n3u: Difference between revisions

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[[Image:1n3u.gif|left|200px]]<br /><applet load="1n3u" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1n3u.gif|left|200px]]
caption="1n3u, resolution 2.58&Aring;" />
 
'''Crystal structure of human heme oxygenase 1 (HO-1) in complex with its substrate heme, crystal form B'''<br />
{{Structure
|PDB= 1n3u |SIZE=350|CAPTION= <scene name='initialview01'>1n3u</scene>, resolution 2.58&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3]
|GENE= HMOX1, HO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human heme oxygenase 1 (HO-1) in complex with its substrate heme, crystal form B'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1N3U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N3U OCA].  
1N3U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N3U OCA].  


==Reference==
==Reference==
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1., Lad L, Schuller DJ, Shimizu H, Friedman J, Li H, Ortiz de Montellano PR, Poulos TL, J Biol Chem. 2003 Mar 7;278(10):7834-43. Epub 2002 Dec 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12500973 12500973]
Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1., Lad L, Schuller DJ, Shimizu H, Friedman J, Li H, Ortiz de Montellano PR, Poulos TL, J Biol Chem. 2003 Mar 7;278(10):7834-43. Epub 2002 Dec 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12500973 12500973]
[[Category: Heme oxygenase]]
[[Category: Heme oxygenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: CL]]
[[Category: CL]]
[[Category: HEM]]
[[Category: HEM]]
[[Category: alpha helices]]
[[Category: alpha helice]]
[[Category: heme-binding site]]
[[Category: heme-binding site]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:01:55 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:51:46 2008''
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