1n8f: Difference between revisions

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[[Image:1n8f.gif|left|200px]]<br /><applet load="1n8f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1n8f.gif|left|200px]]
caption="1n8f, resolution 1.75&Aring;" />
 
'''Crystal structure of E24Q mutant of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Escherichia Coli in complex with Mn2+ and PEP'''<br />
{{Structure
|PDB= 1n8f |SIZE=350|CAPTION= <scene name='initialview01'>1n8f</scene>, resolution 1.75&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54]
|GENE= AroG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal structure of E24Q mutant of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Escherichia Coli in complex with Mn2+ and PEP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1N8F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=PEP:'>PEP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N8F OCA].  
1N8F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N8F OCA].  


==Reference==
==Reference==
The high-resolution structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase reveals a twist in the plane of bound phosphoenolpyruvate., Shumilin IA, Bauerle R, Kretsinger RH, Biochemistry. 2003 Apr 8;42(13):3766-76. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12667068 12667068]
The high-resolution structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase reveals a twist in the plane of bound phosphoenolpyruvate., Shumilin IA, Bauerle R, Kretsinger RH, Biochemistry. 2003 Apr 8;42(13):3766-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12667068 12667068]
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: (beta/alpha)8 barrel]]
[[Category: (beta/alpha)8 barrel]]


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