3oxw: Difference between revisions

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~~[[Image:3oxw.png|left|200px]]~~

==Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir==

~~{{STRUCTURE_3oxw| PDB=3oxw | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3oxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_arv2/sf2 Hiv-1 m:b_arv2/sf2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXW OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OXW FirstGlance].

===Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir===

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3oxv|3oxv]], [[3oy4|3oy4]], [[3oxx|3oxx]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11685 HIV-1 M:B_ARV2/SF2])</td></tr>

==~~About this Structure~~==

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </td></tr>

[[3oxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_arv2/sf2 Hiv-1 m:b_arv2/sf2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXW OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oxw RCSB], [http://www.ebi.ac.uk/pdbsum/3oxw PDBsum]</td></tr>

</table>

==See Also==

*[[Virus protease|Virus protease]]

__TOC__

</StructureSection>

[[Category: HIV-1 retropepsin]]

[[Category: Hiv-1 m:b_arv2/sf2]]

[[Category: Bandaranayake, R M.]]

[[Category: Bandaranayake, R M]]

[[Category: Mittal, S.]]

[[Category: Mittal, S]]

[[Category: Schiffer, C A.]]

[[Category: Schiffer, C A]]

[[Category: Aid]]

[[Category: Aspartyl protease]]

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@@ Line 1: / Line 1: @@
-[[Image:3oxw.png|left|200px]]
+==Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir==
+<StructureSection load='3oxw' size='340' side='right' caption='[[3oxw]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-{{STRUCTURE_3oxw|  PDB=3oxw  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3oxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_arv2/sf2 Hiv-1 m:b_arv2/sf2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OXW FirstGlance]. <br>
-===Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir===
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3oxv|3oxv]], [[3oy4|3oy4]], [[3oxx|3oxx]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11685 HIV-1 M:B_ARV2/SF2])</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
-[[3oxw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_arv2/sf2 Hiv-1 m:b_arv2/sf2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OXW OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oxw RCSB], [http://www.ebi.ac.uk/pdbsum/3oxw PDBsum]</span></td></tr>
+</table>
 ==See Also==
 *[[Virus protease|Virus protease]]
+__TOC__
+</StructureSection>
 [[Category: HIV-1 retropepsin]]
 [[Category: Hiv-1 m:b_arv2/sf2]]
-[[Category: Bandaranayake, R M.]]
+[[Category: Bandaranayake, R M]]
-[[Category: Mittal, S.]]
+[[Category: Mittal, S]]
-[[Category: Schiffer, C A.]]
+[[Category: Schiffer, C A]]
 [[Category: Aid]]
 [[Category: Aspartyl protease]]