3o6o: Difference between revisions
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==Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of an the inhibitor BIIB021== | |||
<StructureSection load='3o6o' size='340' side='right' caption='[[3o6o]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3o6o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6O FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=94M:6-CHLORO-9-[(4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYL]-9H-PURIN-2-AMINE'>94M</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb10.26.1080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5691 Trypanosoma brucei])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o6o RCSB], [http://www.ebi.ac.uk/pdbsum/3o6o PDBsum]</span></td></tr> | |||
== | </table> | ||
[[3o6o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6O OCA]. | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o6/3o6o_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Heat Shock Proteins|Heat Shock Proteins]] | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Trypanosoma brucei]] | [[Category: Trypanosoma brucei]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bochkarev, A | [[Category: Bochkarev, A]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Cossar, D | [[Category: Cossar, D]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Fairlamb, A H | [[Category: Fairlamb, A H]] | ||
[[Category: Ferguson, M A.J]] | [[Category: Ferguson, M A.J]] | ||
[[Category: Hills, T | [[Category: Hills, T]] | ||
[[Category: Hui, R | [[Category: Hui, R]] | ||
[[Category: Hutchinson, A | [[Category: Hutchinson, A]] | ||
[[Category: Kozieradzki, I | [[Category: Kozieradzki, I]] | ||
[[Category: Li, Y | [[Category: Li, Y]] | ||
[[Category: MacKenzie, C | [[Category: MacKenzie, C]] | ||
[[Category: Pizarro, J C | [[Category: Pizarro, J C]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Sullivan, H | [[Category: Sullivan, H]] | ||
[[Category: Thompson, S | [[Category: Thompson, S]] | ||
[[Category: Weadge, J | [[Category: Weadge, J]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Wernimont, A K | [[Category: Wernimont, A K]] | ||
[[Category: Wyatt, P | [[Category: Wyatt, P]] | ||
[[Category: African sleeping sickness]] | [[Category: African sleeping sickness]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Heat shock protein]] | [[Category: Heat shock protein]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Trypanosoma]] | [[Category: Trypanosoma]] | ||
Revision as of 11:50, 9 December 2014
Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of an the inhibitor BIIB021
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Trypanosoma brucei
- Arrowsmith, C H
- Bochkarev, A
- Bountra, C
- Cossar, D
- Edwards, A M
- Fairlamb, A H
- Ferguson, M A.J
- Hills, T
- Hui, R
- Hutchinson, A
- Kozieradzki, I
- Li, Y
- MacKenzie, C
- Pizarro, J C
- Structural genomic
- Sullivan, H
- Thompson, S
- Weadge, J
- Weigelt, J
- Wernimont, A K
- Wyatt, P
- African sleeping sickness
- Chaperone
- Heat shock protein
- Sgc
- Trypanosoma
