1nch: Difference between revisions
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[[Image:1nch.gif|left|200px]] | [[Image:1nch.gif|left|200px]] | ||
'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS''' | {{Structure | ||
|PDB= 1nch |SIZE=350|CAPTION= <scene name='initialview01'>1nch</scene>, resolution 2.1Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=YB:YTTERBIUM (III) ION'>YB</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1NCH is a [ | 1NCH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCH OCA]. | ||
==Reference== | ==Reference== | ||
Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:[http:// | Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7885471 7885471] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: cadherin]] | [[Category: cadherin]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:55:06 2008'' | ||
Revision as of 10:55, 20 March 2008
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| 1nch, resolution 2.1Å | |||||||||||||
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| Ligands: | YB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Overview
Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.
About this Structure
1NCH is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471
Page seeded by OCA on Thu Mar 20 12:55:06 2008
