3okj: Difference between revisions
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==Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition== | |||
<StructureSection load='3okj' size='340' side='right' caption='[[3okj]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3okj]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OKJ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EP9:N-[(BENZYLOXY)CARBONYL]-L-LEUCYL-N-[(2S,3S)-3-HYDROXY-1-(4-HYDROXYPHENYL)-4-OXOBUTAN-2-YL]-L-LEUCINAMIDE'>EP9</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ryp|1ryp]], [[1j2q|1j2q]], [[3d29|3d29]], [[1g65|1g65]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proteasome_endopeptidase_complex Proteasome endopeptidase complex], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.25.1 3.4.25.1] </span></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3okj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3okj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3okj RCSB], [http://www.ebi.ac.uk/pdbsum/3okj PDBsum]</span></td></tr> | ||
[[3okj]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKJ OCA]. | </table> | ||
==See Also== | ==See Also== | ||
*[[Proteasome|Proteasome]] | *[[Proteasome|Proteasome]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Proteasome endopeptidase complex]] | [[Category: Proteasome endopeptidase complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Gallastegui, P | [[Category: Gallastegui, P]] | ||
[[Category: Groll, M | [[Category: Groll, M]] | ||
[[Category: Huber, R | [[Category: Huber, R]] | ||
[[Category: Kloetzel, PM | [[Category: Kloetzel, PM]] | ||
[[Category: Poynor, M | [[Category: Poynor, M]] | ||
[[Category: Schmidt, B | [[Category: Schmidt, B]] | ||
[[Category: Stein, M | [[Category: Stein, M]] | ||
[[Category: Central antiparallel beta-sheet flanked by helice]] | [[Category: Central antiparallel beta-sheet flanked by helice]] | ||
[[Category: Cytosol]] | [[Category: Cytosol]] | ||
