3oy4: Difference between revisions

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~~[[Image:3oy4.png|left|200px]]~~

==Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.==

~~{{STRUCTURE_3oy4| PDB=3oy4 | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OY4 FirstGlance].

===Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.===

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3oxv|3oxv]], [[3oxw|3oxw]], [[3oxx|3oxx]]</td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>

==~~About this Structure~~==

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </td></tr>

[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA].

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oy4 RCSB], [http://www.ebi.ac.uk/pdbsum/3oy4 PDBsum]</td></tr>

</table>

==See Also==

*[[Virus protease|Virus protease]]

__TOC__

</StructureSection>

[[Category: HIV-1 retropepsin]]

[[Category: Human immunodeficiency virus 1]]

[[Category: Bandaranayake, R M.]]

[[Category: Bandaranayake, R M]]

[[Category: Nalivaika, E A.]]

[[Category: Nalivaika, E A]]

[[Category: Schiffer, C A.]]

[[Category: Schiffer, C A]]

[[Category: Aid]]

[[Category: Aspartyl protease]]

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-[[Image:3oy4.png|left|200px]]
+==Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.==
+<StructureSection load='3oy4' size='340' side='right' caption='[[3oy4]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
-{{STRUCTURE_3oy4|  PDB=3oy4  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OY4 FirstGlance]. <br>
-===Crystal Structure of HIV-1 L76V Protease in Complex with the Protease Inhibitor Darunavir.===
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3oxv|3oxv]], [[3oxw|3oxw]], [[3oxx|3oxx]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span></td></tr>
-[[3oy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OY4 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oy4 RCSB], [http://www.ebi.ac.uk/pdbsum/3oy4 PDBsum]</span></td></tr>
+</table>
 ==See Also==
 *[[Virus protease|Virus protease]]
+__TOC__
+</StructureSection>
 [[Category: HIV-1 retropepsin]]
 [[Category: Human immunodeficiency virus 1]]
-[[Category: Bandaranayake, R M.]]
+[[Category: Bandaranayake, R M]]
-[[Category: Nalivaika, E A.]]
+[[Category: Nalivaika, E A]]
-[[Category: Schiffer, C A.]]
+[[Category: Schiffer, C A]]
 [[Category: Aid]]
 [[Category: Aspartyl protease]]