1nx9: Difference between revisions

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[[Image:1nx9.gif|left|200px]]<br /><applet load="1nx9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nx9.gif|left|200px]]
caption="1nx9, resolution 2.20&Aring;" />
 
'''Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin'''<br />
{{Structure
|PDB= 1nx9 |SIZE=350|CAPTION= <scene name='initialview01'>1nx9</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=AIC:(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC+ACID'>AIC</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amino-acid_esterase Alpha-amino-acid esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.43 3.1.1.43]
|GENE=
}}
 
'''Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NX9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Acetobacter_pasteurianus Acetobacter pasteurianus] with <scene name='pdbligand=AIC:'>AIC</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-amino-acid_esterase Alpha-amino-acid esterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.43 3.1.1.43] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NX9 OCA].  
1NX9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Acetobacter_pasteurianus Acetobacter pasteurianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NX9 OCA].  


==Reference==
==Reference==
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme., Barends TR, Polderman-Tijmes JJ, Jekel PA, Williams C, Wybenga G, Janssen DB, Dijkstra BW, J Biol Chem. 2006 Mar 3;281(9):5804-10. Epub 2005 Dec 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16377627 16377627]
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme., Barends TR, Polderman-Tijmes JJ, Jekel PA, Williams C, Wybenga G, Janssen DB, Dijkstra BW, J Biol Chem. 2006 Mar 3;281(9):5804-10. Epub 2005 Dec 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16377627 16377627]
[[Category: Acetobacter pasteurianus]]
[[Category: Acetobacter pasteurianus]]
[[Category: Alpha-amino-acid esterase]]
[[Category: Alpha-amino-acid esterase]]
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[[Category: jellyroll]]
[[Category: jellyroll]]


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