1ny0: Difference between revisions

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[[Image:1ny0.gif|left|200px]]<br /><applet load="1ny0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ny0.gif|left|200px]]
caption="1ny0, resolution 1.75&Aring;" />
 
'''Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (NBF)'''<br />
{{Structure
|PDB= 1ny0 |SIZE=350|CAPTION= <scene name='initialview01'>1ny0</scene>, resolution 1.75&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=NBF:[(2-ETHOXY-1-NAPHTHOYL)AMINO]METHYLBORONIC ACID'>NBF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]
|GENE= bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (NBF)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NY0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=NBF:'>NBF</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NY0 OCA].  
1NY0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NY0 OCA].  


==Reference==
==Reference==
Recognition and resistance in TEM beta-lactamase., Wang X, Minasov G, Blazquez J, Caselli E, Prati F, Shoichet BK, Biochemistry. 2003 Jul 22;42(28):8434-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12859188 12859188]
Recognition and resistance in TEM beta-lactamase., Wang X, Minasov G, Blazquez J, Caselli E, Prati F, Shoichet BK, Biochemistry. 2003 Jul 22;42(28):8434-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12859188 12859188]
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: crystal structure]]
[[Category: crystal structure]]


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