1ol1: Difference between revisions

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[[Image:1ol1.gif|left|200px]]<br /><applet load="1ol1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ol1.gif|left|200px]]
caption="1ol1, resolution 2.9&Aring;" />
 
'''CYCLIN A BINDING GROOVE INHIBITOR H-CIT-CIT-LEU-ILE-(P-F-PHE)-NH2'''<br />
{{Structure
|PDB= 1ol1 |SIZE=350|CAPTION= <scene name='initialview01'>1ol1</scene>, resolution 2.9&Aring;
|SITE= <scene name='pdbsite=CBG:Cyclin+Binding+Groove+Chain+D'>CBG</scene>
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]
|GENE=
}}
 
'''CYCLIN A BINDING GROOVE INHIBITOR H-CIT-CIT-LEU-ILE-(P-F-PHE)-NH2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OL1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37] Known structural/functional Site: <scene name='pdbsite=CBG:Cyclin+Binding+Groove+Chain+D'>CBG</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OL1 OCA].  
1OL1 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OL1 OCA].  


==Reference==
==Reference==
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14656438 14656438]
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14656438 14656438]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: cell cycle]]
[[Category: cell cycle]]
[[Category: cell division]]
[[Category: cell division]]
[[Category: cyclin a]]
[[Category: cyclin some]]
[[Category: drug design]]
[[Category: drug design]]
[[Category: inhibitor]]
[[Category: inhibitor]]
[[Category: ligand exchange]]
[[Category: ligand exchange]]
[[Category: mitosis]]
[[Category: mitosis]]
[[Category: peptidomimetics]]
[[Category: peptidomimetic]]
[[Category: phosphorylation]]
[[Category: phosphorylation]]
[[Category: transfera serine/threonine-protein kinase]]
[[Category: transfera serine/threonine-protein kinase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:18:55 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:12:20 2008''
Retrieved from "https://proteopedia.org/1ol1"