1os5: Difference between revisions

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[[Image:1os5.jpg|left|200px]]<br /><applet load="1os5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1os5.jpg|left|200px]]
caption="1os5, resolution 2.2&Aring;" />
 
'''Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor.'''<br />
{{Structure
|PDB= 1os5 |SIZE=350|CAPTION= <scene name='initialview01'>1os5</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NH1:3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE'>NH1</scene>
|ACTIVITY=
|GENE= NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=42791 Hepatitis C virus subtype 3b])
}}
 
'''Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OS5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_3b Hepatitis c virus subtype 3b] with <scene name='pdbligand=NH1:'>NH1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OS5 OCA].  
1OS5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_3b Hepatitis c virus subtype 3b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OS5 OCA].  


==Reference==
==Reference==
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme., Love RA, Parge HE, Yu X, Hickey MJ, Diehl W, Gao J, Wriggers H, Ekker A, Wang L, Thomson JA, Dragovich PS, Fuhrman SA, J Virol. 2003 Jul;77(13):7575-81. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12805457 12805457]
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme., Love RA, Parge HE, Yu X, Hickey MJ, Diehl W, Gao J, Wriggers H, Ekker A, Wang L, Thomson JA, Dragovich PS, Fuhrman SA, J Virol. 2003 Jul;77(13):7575-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12805457 12805457]
[[Category: Hepatitis c virus subtype 3b]]
[[Category: Hepatitis c virus subtype 3b]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: enzyme-inhibitor complex]]
[[Category: enzyme-inhibitor complex]]


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Retrieved from "https://proteopedia.org/1os5"