Thiolase: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 2: Line 2:


Two different classes of '''thiolases''' are found .  Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA.
Two different classes of '''thiolases''' are found .  Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA.
{{TOC limit|limit=2}}


For Bacterial Thiolase see [[Bacterial thiolase]]
For Bacterial Thiolase see [[Bacterial thiolase]]
Line 9: Line 8:


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


===3-ketoacyl-CoA thiolase===
*3-ketoacyl-CoA thiolase


[[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br />
**[[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br />
[[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br />
**[[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br />
[[2iik]] – hKCT peroximal - human<br />
**[[2iik]] – hKCT peroximal - human<br />
[[3goa]] – KCT – ''Salmonella typhimurium''<br />
**[[3goa]] – KCT – ''Salmonella typhimurium''<br />
[[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br />
**[[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br />
[[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br />
**[[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br />
[[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br />
**[[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br />
[[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit
**[[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit


===Acetoacetyl-CoA thiolase===
*Acetoacetyl-CoA thiolase
 
[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br />
[[1dm3]], [[1dlv]] – ZrACT + CoA<br />
[[2wku]], [[2wl6]], [[1m1t]], [[1m3k]] - ZrACT (mutant) <br />
[[2wkt]], [[2wkv]], [[2wl4]], [[2wl5]], [[2vtz]], [[2vu0]], [[1m3z]] – ZrACT (mutant) + CoA<br />
[[1m1o]] - ZrACT (mutant) + acetoacetyl-CoA<br />
[[2vu0]], [[1nl7]] - ZrACT + CoA<br />
[[2vu1]], [[2vu2]], [[1ou6]] - ZrACT + pantheteine-11-pivalate<br />
[[2ib7]], [[2ib8]], [[2ib9]], [[2ibu]], [[2ibw]], [[2iby]], [[2f2s]] – hACT mitochondrial<br />
[[1wl5]] - hACT cytosolic<br />
[[1wl4]] – hACT cytosolic + CoA<br />
[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br />


**[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br />
**[[1dm3]], [[1dlv]] – ZrACT + CoA<br />
**[[2wku]], [[2wl6]], [[1m1t]], [[1m3k]] - ZrACT (mutant) <br />
**[[2wkt]], [[2wkv]], [[2wl4]], [[2wl5]], [[2vtz]], [[2vu0]], [[1m3z]] – ZrACT (mutant) + CoA<br />
**[[1m1o]] - ZrACT (mutant) + acetoacetyl-CoA<br />
**[[2vu0]], [[1nl7]] - ZrACT + CoA<br />
**[[2vu1]], [[2vu2]], [[1ou6]] - ZrACT + pantheteine-11-pivalate<br />
**[[2ib7]], [[2ib8]], [[2ib9]], [[2ibu]], [[2ibw]], [[2iby]], [[2f2s]] – hACT mitochondrial<br />
**[[1wl5]] - hACT cytosolic<br />
**[[1wl4]] – hACT cytosolic + CoA<br />
**[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br />
}}


[[Category:Topic Page]]
[[Category:Topic Page]]