Thiolase: Difference between revisions
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Two different classes of '''thiolases''' are found . Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA. | Two different classes of '''thiolases''' are found . Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA. | ||
For Bacterial Thiolase see [[Bacterial thiolase]] | For Bacterial Thiolase see [[Bacterial thiolase]] | ||
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | |||
*3-ketoacyl-CoA thiolase | |||
[[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br /> | **[[2wu9]], [[2c7y]], [[2c7z]] – KCT peroxisomal residues 36-462 – ''Arabidopsis thaliana''<br /> | ||
[[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br /> | **[[2wua]] - KCT peroxisomal residues 17-449 (mutant) – sunflower<br /> | ||
[[2iik]] – hKCT peroximal - human<br /> | **[[2iik]] – hKCT peroximal - human<br /> | ||
[[3goa]] – KCT – ''Salmonella typhimurium''<br /> | **[[3goa]] – KCT – ''Salmonella typhimurium''<br /> | ||
[[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br /> | **[[1afw]], [[1pxt]] – yKCT peroxisomal - yeast<br /> | ||
[[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br /> | **[[3w15]] - yKCT peroxisomal residues 27-396 + peroxiomal membrane protein PEX21 + peroxisomal targeting signal receptor<br /> | ||
[[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br /> | **[[2d3t]] – PfKCT + fatty oxidation complex β subunit – ''Pseudomonas fragi''<br /> | ||
[[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit | **[[1wdk]], [[1wdl]], [[1wdm]] - PfKCT + fatty oxidation complex α subunit | ||
*Acetoacetyl-CoA thiolase | |||
**[[1m4s]], [[1m4t]], [[1dlu]], [[1qfl]] - ZrACT – ''Zoogloea ramigera''<br /> | |||
**[[1dm3]], [[1dlv]] – ZrACT + CoA<br /> | |||
**[[2wku]], [[2wl6]], [[1m1t]], [[1m3k]] - ZrACT (mutant) <br /> | |||
**[[2wkt]], [[2wkv]], [[2wl4]], [[2wl5]], [[2vtz]], [[2vu0]], [[1m3z]] – ZrACT (mutant) + CoA<br /> | |||
**[[1m1o]] - ZrACT (mutant) + acetoacetyl-CoA<br /> | |||
**[[2vu0]], [[1nl7]] - ZrACT + CoA<br /> | |||
**[[2vu1]], [[2vu2]], [[1ou6]] - ZrACT + pantheteine-11-pivalate<br /> | |||
**[[2ib7]], [[2ib8]], [[2ib9]], [[2ibu]], [[2ibw]], [[2iby]], [[2f2s]] – hACT mitochondrial<br /> | |||
**[[1wl5]] - hACT cytosolic<br /> | |||
**[[1wl4]] – hACT cytosolic + CoA<br /> | |||
**[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br /> | |||
}} | |||
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