1p1r: Difference between revisions

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[[Image:1p1r.gif|left|200px]]<br /><applet load="1p1r" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p1r.gif|left|200px]]
caption="1p1r, resolution 1.57&Aring;" />
 
'''Horse liver alcohol dehydrogenase complexed with NADH and R-N-1-methylhexylformamide'''<br />
{{Structure
|PDB= 1p1r |SIZE=350|CAPTION= <scene name='initialview01'>1p1r</scene>, resolution 1.57&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=NAJ:NICOTINAMIDE-ADENINE-DINUCLEOTIDE+(ACIDIC+FORM)'>NAJ</scene>, <scene name='pdbligand=NMH:(R)-N-(1-METHYL-HEXYL)-FORMAMIDE'>NMH</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1]
|GENE=
}}
 
'''Horse liver alcohol dehydrogenase complexed with NADH and R-N-1-methylhexylformamide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1P1R is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NAJ:'>NAJ</scene>, <scene name='pdbligand=NMH:'>NMH</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1R OCA].  
1P1R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1R OCA].  


==Reference==
==Reference==
Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism., Venkataramaiah TH, Plapp BV, J Biol Chem. 2003 Sep 19;278(38):36699-706. Epub 2003 Jul 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12855684 12855684]
Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism., Venkataramaiah TH, Plapp BV, J Biol Chem. 2003 Sep 19;278(38):36699-706. Epub 2003 Jul 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12855684 12855684]
[[Category: Alcohol dehydrogenase]]
[[Category: Alcohol dehydrogenase]]
[[Category: Equus caballus]]
[[Category: Equus caballus]]
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[[Category: puckered reduced nicotinamide ring]]
[[Category: puckered reduced nicotinamide ring]]


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Retrieved from "https://proteopedia.org/1p1r"