1p6b: Difference between revisions

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[[Image:1p6b.jpg|left|200px]]~~<br /><applet load~~="1p6b~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1p6b.jpg|left|200px]]

~~caption="~~1p6b, resolution 1.90Å" />

'''X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T'''~~<br />~~

{{Structure

|PDB= 1p6b |SIZE=350|CAPTION= <scene name='initialview01'>1p6b</scene>, resolution 1.90Å

|SITE=

|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=EBP:DIETHYL+4-METHYLBENZYLPHOSPHONATE'>EBP</scene> and <scene name='pdbligand=EFS:ETHYL DIHYDROGEN PHOSPHATE'>EFS</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1]

|GENE= OPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=239 Flavobacterium sp.])

}}

'''X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T'''

==Overview==

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==About this Structure==

1P6B is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Flavobacterium_sp. Flavobacterium sp.] ~~with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=EBP:'>EBP</scene> and <scene name='pdbligand=EFS:'>EFS</scene> as [http://en.wikipedia~~.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P6B OCA].

1P6B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Flavobacterium_sp. Flavobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P6B OCA].

==Reference==

Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site., Hill CM, Li WS, Thoden JB, Holden HM, Raushel FM, J Am Chem Soc. 2003 Jul 30;125(30):8990-1. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~15369336 15369336]

Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site., Hill CM, Li WS, Thoden JB, Holden HM, Raushel FM, J Am Chem Soc. 2003 Jul 30;125(30):8990-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15369336 15369336]

[[Category: Aryldialkylphosphatase]]

[[Category: Flavobacterium sp.]]

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[[Category: ZN]]

[[Category: metalloenzyme]]

[[Category: nerve ~~agents~~]]

[[Category: nerve agent]]

[[Category: tim barrel]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 14~~:25~~:34~~ 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:20:25 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1p6b.jpg|left|200px]]<br /><applet load="1p6b" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1p6b.jpg|left|200px]]
-caption="1p6b, resolution 1.90&Aring;" />
-'''X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T'''<br />
+ {{Structure
+|PDB= 1p6b |SIZE=350|CAPTION= <scene name='initialview01'>1p6b</scene>, resolution 1.90&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=EBP:DIETHYL+4-METHYLBENZYLPHOSPHONATE'>EBP</scene> and <scene name='pdbligand=EFS:ETHYL DIHYDROGEN PHOSPHATE'>EFS</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1]
+|GENE= OPD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=239 Flavobacterium sp.])
+}}
+'''X-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-P6B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Flavobacterium_sp. Flavobacterium sp.] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=EBP:'>EBP</scene> and <scene name='pdbligand=EFS:'>EFS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P6B OCA].
+P6B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Flavobacterium_sp. Flavobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P6B OCA].
 ==Reference==
-Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site., Hill CM, Li WS, Thoden JB, Holden HM, Raushel FM, J Am Chem Soc. 2003 Jul 30;125(30):8990-1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15369336 15369336]
+Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site., Hill CM, Li WS, Thoden JB, Holden HM, Raushel FM, J Am Chem Soc. 2003 Jul 30;125(30):8990-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15369336 15369336]
 [[Category: Aryldialkylphosphatase]]
 [[Category: Flavobacterium sp.]]
@@ Line 23: / Line 32: @@
 [[Category: ZN]]
 [[Category: metalloenzyme]]
-[[Category: nerve agents]]
+[[Category: nerve agent]]
 [[Category: tim barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:25:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:20:25 2008''