1p8f: Difference between revisions

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[[Image:1p8f.jpg|left|200px]]<br /><applet load="1p8f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1p8f.jpg|left|200px]]
caption="1p8f, resolution 1.85&Aring;" />
 
'''A four location model to explain the stereospecificity of proteins.'''<br />
{{Structure
|PDB= 1p8f |SIZE=350|CAPTION= <scene name='initialview01'>1p8f</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42]
|GENE= ICD OR ICDA OR ICDE OR B1136 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''A four location model to explain the stereospecificity of proteins.'''
 


==About this Structure==
==About this Structure==
1P8F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ICT:'>ICT</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8F OCA].  
1P8F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8F OCA].  


==Reference==
==Reference==
A new model for protein stereospecificity., Mesecar AD, Koshland DE Jr, Nature. 2000 Feb 10;403(6770):614-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10688187 10688187]
A new model for protein stereospecificity., Mesecar AD, Koshland DE Jr, Nature. 2000 Feb 10;403(6770):614-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10688187 10688187]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Isocitrate dehydrogenase (NADP(+))]]
[[Category: Isocitrate dehydrogenase (NADP(+))]]
Line 26: Line 35:
[[Category: stereospecificity]]
[[Category: stereospecificity]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:26:33 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:21:16 2008''

Revision as of 11:21, 20 March 2008

File:1p8f.jpg


Drag the structure with the mouse to rotate
1p8f, resolution 1.85Å
Ligands: SO4, MG, ICT and GOL
Gene: ICD OR ICDA OR ICDE OR B1136 (Escherichia coli)
Activity: Isocitrate dehydrogenase (NADP(+)), with EC number 1.1.1.42
Coordinates: save as pdb, mmCIF, xml



A four location model to explain the stereospecificity of proteins.


About this Structure

1P8F is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

A new model for protein stereospecificity., Mesecar AD, Koshland DE Jr, Nature. 2000 Feb 10;403(6770):614-5. PMID:10688187

Page seeded by OCA on Thu Mar 20 13:21:16 2008

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