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{{STRUCTURE_3ihk|  PDB=3ihk  |  SCENE=  }}
==Crystal Structure of thiamin pyrophosphokinase from S.mutans, Northeast Structural Genomics Consortium Target SmR83==
===Crystal Structure of thiamin pyrophosphokinase from S.mutans, Northeast Structural Genomics Consortium Target SmR83===
<StructureSection load='3ihk' size='340' side='right' caption='[[3ihk]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3ihk]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IHK FirstGlance]. <br>
[[3ihk]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IHK OCA].  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SMU_353 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ihk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ihk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ihk RCSB], [http://www.ebi.ac.uk/pdbsum/3ihk PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ih/3ihk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Streptococcus mutans]]
[[Category: Streptococcus mutans]]
[[Category: Abashidze, M.]]
[[Category: Abashidze, M]]
[[Category: Acton, T B.]]
[[Category: Acton, T B]]
[[Category: Ciccosanti,C.]]
[[Category: Ciccosanti,C]]
[[Category: Everett, J K.]]
[[Category: Everett, J K]]
[[Category: Foote,E L.]]
[[Category: Foote,E L]]
[[Category: Hunt,J F.]]
[[Category: Hunt,J F]]
[[Category: Kuzin,A.]]
[[Category: Kuzin,A]]
[[Category: Maglaqui,M.]]
[[Category: Maglaqui,M]]
[[Category: Mao,M.]]
[[Category: Mao,M]]
[[Category: Montelione, G T.]]
[[Category: Montelione, G T]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Nair, R.]]
[[Category: Nair, R]]
[[Category: Rost, B.]]
[[Category: Rost, B]]
[[Category: Seetharaman,J.]]
[[Category: Seetharaman,J]]
[[Category: Tong,L.]]
[[Category: Tong,L]]
[[Category: Vorobiev,S.]]
[[Category: Vorobiev,S]]
[[Category: Xiao,R.]]
[[Category: Xiao,R]]
[[Category: Zhao,L.]]
[[Category: Zhao,L]]
[[Category: Nesg]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: PSI, Protein structure initiative]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Q8dvv9]]
[[Category: Q8dvv9]]
[[Category: Smr83]]
[[Category: Smr83]]
[[Category: Structural genomic]]
[[Category: Thiamin pyrophosphokinase]]
[[Category: Thiamin pyrophosphokinase]]
[[Category: Transferase]]
[[Category: Transferase]]