1pf8: Difference between revisions

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[[Image:1pf8.gif|left|200px]]<br /><applet load="1pf8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pf8.gif|left|200px]]
caption="1pf8, resolution 2.51&Aring;" />
 
'''Crystal Structure of Human Cyclin-Dependent Kinase 2 Complexed with a Nucleoside Inhibitor'''<br />
{{Structure
|PDB= 1pf8 |SIZE=350|CAPTION= <scene name='initialview01'>1pf8</scene>, resolution 2.51&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SU9:(3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE'>SU9</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= CDK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of Human Cyclin-Dependent Kinase 2 Complexed with a Nucleoside Inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PF8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SU9:'>SU9</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PF8 OCA].  
1PF8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PF8 OCA].  


==Reference==
==Reference==
SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2., Moshinsky DJ, Bellamacina CR, Boisvert DC, Huang P, Hui T, Jancarik J, Kim SH, Rice AG, Biochem Biophys Res Commun. 2003 Oct 24;310(3):1026-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14550307 14550307]
SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2., Moshinsky DJ, Bellamacina CR, Boisvert DC, Huang P, Hui T, Jancarik J, Kim SH, Rice AG, Biochem Biophys Res Commun. 2003 Oct 24;310(3):1026-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14550307 14550307]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]


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