4aka: Difference between revisions
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==IPSE alpha-1, an IgE-binding crystallin== | |||
<StructureSection load='4aka' size='340' side='right' caption='[[4aka]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4aka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AKA FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aka OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aka RCSB], [http://www.ebi.ac.uk/pdbsum/4aka PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) is a major immunogenic component of schistosomes. It potently triggers the release of interleukin-4 from basophilic granulocytes in an IgE-dependent manner, suggesting a key function in the modulation of the host's immune response to Schistosoma mansoni infection. Here we present the near complete assignment of an IPSE/alpha-1 variant, IPSEDeltaNLS, which comprises the core domain of the protein. | |||
1H, 13C and 15N chemical shift assignments of IPSEDeltaNLS.,Meyer NH, Schramm G, Sattler M Biomol NMR Assign. 2011 Oct;5(2):225-7. doi: 10.1007/s12104-011-9305-6. Epub 2011, Apr 24. PMID:21516468<ref>PMID:21516468</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
[[Category: Bade, S | [[Category: Bade, S]] | ||
[[Category: Barths, D | [[Category: Barths, D]] | ||
[[Category: Blindow, S | [[Category: Blindow, S]] | ||
[[Category: Frey, A | [[Category: Frey, A]] | ||
[[Category: Haas, H | [[Category: Haas, H]] | ||
[[Category: Madl, T | [[Category: Madl, T]] | ||
[[Category: Mayerhofer, H | [[Category: Mayerhofer, H]] | ||
[[Category: Meyer, N H | [[Category: Meyer, N H]] | ||
[[Category: Mueller-Dieckmann, J | [[Category: Mueller-Dieckmann, J]] | ||
[[Category: Sattler, M | [[Category: Sattler, M]] | ||
[[Category: Scharmm, G | [[Category: Scharmm, G]] | ||
[[Category: Tripsianes, K | [[Category: Tripsianes, K]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Immunoglobulin binding]] | [[Category: Immunoglobulin binding]] | ||
