1pfg: Difference between revisions

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[[Image:1pfg.jpg|left|200px]]<br /><applet load="1pfg" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1pfg.jpg|left|200px]]
caption="1pfg, resolution 2.5&Aring;" />
 
'''Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution'''<br />
{{Structure
|PDB= 1pfg |SIZE=350|CAPTION= <scene name='initialview01'>1pfg</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64]
|GENE=
}}
 
'''Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1PFG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFG OCA].  
1PFG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFG OCA].  


==Reference==
==Reference==
Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5 A resolution., Saxena AK, Singh TP, Peters K, Fittkau S, Betzel C, Protein Sci. 1996 Dec;5(12):2453-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8976553 8976553]
Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5 A resolution., Saxena AK, Singh TP, Peters K, Fittkau S, Betzel C, Protein Sci. 1996 Dec;5(12):2453-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8976553 8976553]
[[Category: Engyodontium album]]
[[Category: Engyodontium album]]
[[Category: Peptidase K]]
[[Category: Peptidase K]]
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[[Category: proteinase k]]
[[Category: proteinase k]]


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